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Refractometers for Bioprocessing
Real-time concentration monitoring in bioprocessing with KxS inline refractometers.
An inline refractometer for bioprocessing gives the real-time concentration of dissolved solids in a bioreactor feed, harvest or purification stream, without sampling. The KxS DCM-20 comes with an Ingold or sanitary connection, meets 3-A design standards and is EHEDG certified for cleanable bioprocess lines.
1 Product · Bioprocessing
Selection guide
Refractometers for Bioprocessing Guide
What an inline refractometer is used for in bioprocessing
Bioprocesses depend on precise concentrations at several stages: media preparation, fermentation feeds, harvest and purification. An inline refractometer reads the concentration of dissolved solids directly in the pipe, in real time, so an operator or control loop can react immediately rather than waiting for a lab sample.
How to choose a refractometer for bioprocessing
- Connection: the DCM-20 is available with an Ingold or sanitary process connection to match your vessel or line fitting.
- Hygiene: it meets 3-A design standards and is EHEDG certified, with a single-piece 316L flow cell with no weld joints, so it's cleanable in place.
- Mounting: it mounts in vertical or horizontal pipes without affecting the reading.
- Typical duty: media and feed preparation, yeast extract evaporation, ultrafiltration and concentration steps, and enzyme, vitamin or nutraceutical production.
For cell growth measurement inside the fermenter itself, see biomass and cell growth sensors. For hazardous areas, see our ATEX inline process refractometers.
FAQ
Common questions
What process connection is available for bioreactors?
The DCM-20 for bioprocessing comes with an Ingold or sanitary connection, so it fits directly into standard bioreactor and pipeline fittings without an adapter, and mounts in either a vertical or horizontal run of pipe.
Does the refractometer survive CIP and SIP in a bioreactor line?
Yes. The DCM-20 and its single-piece 316L flow cell are CIP-compatible and EHEDG certified, with no weld joints to trap product, so it cleans in place alongside the rest of a hygienic bioprocess line.
Can it control an evaporator in bioprocessing?
Yes. In yeast extract production, for example, the concentration reading from the DCM-20 drives the steam feed to the evaporator, keeping the outlet at target without manual sampling.
What is the DCM-20 used for in bioprocessing?
Real-time concentration monitoring of dissolved solids in media and feed preparation, yeast extract evaporation, ultrafiltration and concentration steps, and enzyme, vitamin or nutraceutical production, wherever a bioreactor or downstream line needs continuous, sample-free measurement.
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